NeuroSource

eyewire:

Play a game to map the brain at http://eyewire.org/.

Bilingual babies know their grammar by 7 months

Babies as young as seven months can distinguish between, and begin to learn, two languages with vastly different grammatical structures, according to new research from the University of British Columbia and Université Paris Descartes.

Published today in the journal Nature Communications and presented at the 2013 Annual Meeting of the American Association for the Advancement of Science (AAAS) in Boston, the study shows that infants in bilingual environments use pitch and duration cues to discriminate between languages – such as English and Japanese – with opposite word orders.

In English, a function word comes before a content word (the dog, his hat, with friends, for example) and the duration of the content word is longer, while in Japanese or Hindi, the order is reversed, and the pitch of the content word higher.

“By as early as seven months, babies are sensitive to these differences and use these as cues to tell the languages apart,” says UBC psychologist Janet Werker, co-author of the study.

Previous research by Werker and Judit Gervain, a linguist at the Université Paris Descartes and co-author of the new study, showed that babies use frequency of words in speech to discern their significance.

“For example, in English the words ‘the’ and ‘with’ come up a lot more frequently than other words – they’re essentially learning by counting,” says Gervain. “But babies growing up bilingual need more than that, so they develop new strategies that monolingual babies don’t necessarily need to use.”

“If you speak two languages at home, don’t be afraid, it’s not a zero-sum game,” says Werker. “Your baby is very equipped to keep these languages separate and they do so in remarkable ways.”

(Source: neurosciencestuff)

Threat bias interacts with combat, gene to boost PTSD risk

Soldiers preoccupied with threat at the time of enlistment or with avoiding it just before deployment were more likely to develop post-traumatic stress disorder (PTSD), in a study of Israeli infantrymen. Such pre-deployment threat vigilance and avoidance, interacting with combat experience and an emotion-related gene, accounted for more than a third of PTSD symptoms that emerged later, say National Institutes of Health scientists, who conducted the study in collaboration with American and Israeli colleagues.

“Since biased attention predicted future risk for PTSD, computerized training that helps modify such attention biases might help protect soldiers from the disorder,” said Daniel Pine, M.D., of the NIH’s National Institute of Mental Health (NIMH).

Pine, Yair Bar-Haim, Ph.D., of Tel Aviv University, and colleagues, report their findings, Feb.  13, 2013, in the journal JAMA Psychiatry.

(Source: neurosciencestuff)

Evidence Mounts for Role of Mutated Genes in Development of Schizophrenia

Johns Hopkins researchers have identified a rare gene mutation in a single family with a high rate of schizophrenia, adding to evidence that abnormal genes play a role in the development of the disease.

The researchers, in a report published in the journal Molecular Psychiatry, say that family members with the mutation in the gene Neuronal PAS domain protein 3 (NPAS3) appear at high risk of developing schizophrenia or another debilitating mental illnesses.

Normally functioning NPAS3 regulates the development of healthy neurons, especially in a region of the brain known as the hippocampus, which appears to be affected in schizophrenia. The Johns Hopkins researchers say they have evidence that the mutation found in the family may lead to abnormal activity of NPAS3, which has implications for brain development and function.

“Understanding the molecular and biological pathways of schizophrenia is a powerful way to advance the development of treatments that have fewer side effects and work better than the treatments now available,” says study leader Frederick C. Nucifora Jr., Ph.D., D.O., M.H.S., an assistant professor of psychiatry and behavioral sciences at the Johns Hopkins University School of Medicine. “We could definitely use better medicines.”

(Source: neurosciencestuff)

Poor sleep in old age prevents the brain from storing memories

The connection between poor sleep, memory loss and brain deterioration as we grow older has been elusive. But for the first time, scientists at the University of California, Berkeley, have found a link between these hallmark maladies of old age. Their discovery opens the door to boosting the quality of sleep in elderly people to improve memory.

UC Berkeley neuroscientists have found that the slow brain waves generated during the deep, restorative sleep we typically experience in youth play a key role in transporting memories from the hippocampus – which provides short-term storage for memories – to the prefrontal cortex’s longer term “hard drive.”

However, in older adults, memories may be getting stuck in the hippocampus due to the poor quality of deep ‘slow wave’ sleep, and are then overwritten by new memories, the findings suggest.

“What we have discovered is a dysfunctional pathway that helps explain the relationship between brain deterioration, sleep disruption and memory loss as we get older – and with that, a potentially new treatment avenue,” said UC Berkeley sleep researcher Matthew Walker, an associate professor of psychology and neuroscience at UC Berkeley and senior author of the study published in the journal Nature Neuroscience.

(Source: neurosciencestuff)

neurosciencestuff:

Mistaking OCD for ADHD Has Serious Consequences

On the surface, obsessive compulsive disorder (OCD) and attention deficit/hyperactivity disorder (ADHD) appear very similar, with impaired attention, memory, or behavioral control. But Prof. Reuven Dar of Tel Aviv University’s School of Psychological Sciences argues that these two neuropsychological disorders have very different roots — and there are enormous consequences if they are mistaken for each other.

Prof. Dar and fellow researcher Dr. Amitai Abramovitch, who completed his PhD under Prof. Dar’s supervision, have determined that despite appearances, OCD and ADHD are far more different than alike. While groups of both OCD and ADHD patients were found to have difficulty controlling their abnormal impulses in a laboratory setting, only the ADHD group had significant problems with these impulses in the real world.

According to Prof. Dar, this shows that while OCD and ADHD may appear similar on a behavioral level, the mechanism behind the two disorders differs greatly. People with ADHD are impulsive risk-takers, rarely reflecting on the consequences of their actions. In contrast, people with OCD are all too concerned with consequences, causing hesitancy, difficulty in decision-making, and the tendency to over-control and over-plan.

Their findings, published in the Journal of Neuropsychology, draw a clear distinction between OCD and ADHD and provide more accurate guidelines for correct diagnosis. Confusing the two threatens successful patient care, warns Prof. Dar, noting that treatment plans for the two disorders can differ dramatically. Ritalin, a psychostimulant commonly prescribed to ADHD patients, can actually exacerbate OCD behaviors, for example. Prescribed to an OCD patient, it will only worsen symptoms.

kqedscience:

Scientists have found that the brain is wired to put the categories of objects and actions we see daily in order, and have created the first interactive map of how the brain organizes these groupings.

Via Futurity:

http://www.futurity.org/science-technology/interactive-map-how-the-brain-sorts-what-we-see/#

(Source: gallantlab.org, via theolduvaigorge)

neurosciencestuff:

Protein Creates Paths For Growing Nerve Cells

Working with mice, Johns Hopkins scientists have discovered that a particular protein helps nerve cells extend themselves along the spinal cord during mammalian development. Their results shed light on the subset of muscular dystrophies that result from mutations in the gene that holds the code for the protein, called dystroglycan, and also show how the nerve and muscle failings of the degenerative diseases are related.

As mammals like mice and humans develop, nerve cells in the brain and spinal cord must form connections with themselves and with muscles to assure proper control of movement. Nerve cells sometimes extend the whole length of the spinal cord to connect sensory nerves bearing information, for example, from the legs to the brain. To do so, nerve cells anchor their “headquarters,” or cell bodies, in one location, and then extend a long, thin projection all the way to their target locations. These projections, or axons, can be 10,000 times longer than the cell body.

In a report published in the journal Neuron on Dec. 6, the authors suggest that, during fetal development, axons extend themselves along specific pathways created by dystroglycan.

(via theolduvaigorge)

oldowan:

anth-receptor:

oldowan:

neurosciencestuff:

Human hands have ‘evolved for fighting’

Compared with apes, humans have shorter palms and fingers and longer, stronger flexible thumbs. Experts have long assumed these features evolved to help our ancestors make and use tools. But new evidence from the US suggests it was not just dexterity that shaped the human hand, but violence also.

Hands largely evolved through natural selection to form a punching fist, it is claimed. ”The role aggression has played in our evolution has not been adequately appreciated,” said Professor David Carrier, from the University of Utah.

”There are people who do not like this idea but it is clear that compared with other mammals, great apes are a relatively aggressive group with lots of fighting and violence, and that includes us. We’re the poster children for violence.”

The forces of natural selection that drove hands to become nimble-fingered also turned them into weapons, Prof Carrier believes.

”Individuals who could strike with a clenched fish could hit harder without injuring themselves, so they were better able to fight for mates and thus be more likely to reproduce,” he said.

”If a fist posture does provide a performance advantage for punching, the proportions of our hands also may have evolved in response to selection for fighting ability, in addition to selection for dexterity.”

I haven’t read this study. Has anyone else?

Haven’t finished reading everything yet, but it seems interesting, thus far. Here’s the link to the article on the Journal of Evolutionary Biology [x]. Morgan and Carrier give a much better argument for it. While I agree that our hands evolving had a lot to do with bipedalism, I feel it is more of a spandrel because our fighting style would have to had changed due to our different body proportion and strengths overall. Hopefully Morgan and Carrier will continue to do this and compare how fighting differs between the great apes in relation to their body type. I mean, they made an interesting and bold assumption, and I suppose I can see how that made that leap, but all I can say thus far is “interesting.”

Reblogging for opinion

(via theolduvaigorge)

neurosciencestuff:

A new type of nerve cell found in the brain

Scientists at Karolinska Institutet in Sweden, in collaboration with colleagues in Germany and the Netherlands, have identified a previously unknown group of nerve cells in the brain. The nerve cells regulate cardiovascular functions such as heart rhythm and blood pressure. It is hoped that the discovery, which is published in the Journal of Clinical Investigation, will be significant in the long term in the treatment of cardiovascular diseases in humans.

The scientists have managed to identify in mice a previously totally unknown group of nerve cells in the brain. These nerve cells, also known as ‘neurons’, develop in the brain with the aid of thyroid hormone, which is produced in the thyroid gland. Patients in whom the function of the thyroid gland is disturbed and who therefore produce too much or too little thyroid hormone, thus risk developing problems with these nerve cells. This in turn has an effect on the function of the heart, leading to cardiovascular disease.

It is well-known that patients with untreated hyperthyroidism (too high a production of thyroid hormone) or hypothyroidism (too low a production of thyroid hormone) often develop heart problems. It has previously been believed that this was solely a result of the hormone affecting the heart directly. The new study, however, shows that thyroid hormone also affects the heart indirectly, through the newly discovered neurons.

“This discovery opens the possibility of a completely new way of combating cardiovascular disease”, says Jens Mittag, group leader at the Department of Cell and Molecular Biology at Karolinska Institutet. “If we learn how to control these neurons, we will be able to treat certain cardiovascular problems like hypertension through the brain. This is, however, still far in the future. A more immediate conclusion is that it is of utmost importance to identify and treat pregnant women with hypothyroidism, since their low level of thyroid hormone may harm the production of these neurons in the foetus, and this may in the long run cause cardiovascular disorders in the offspring.”

(Image: turbosquid.com)

(via theolduvaigorge)